Sheldon's getting fired forces him to explore what life has to offer outside physics, leaving Leonard to take drastic action to snap his friend out of his funk.
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Fearing he's wasting his time on Penny, Leonard ends up making a connection with Leslie. Meanwhile, Sheldon frets over a change to his hamburger routine.
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Amy and Bernadette accuse former party girl Penny of becoming a party pooper when she lets an email from work impact their girls' weekend in Las Vegas. Meanwhile, the guys brainstorm about inventing something cool.
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Sheldon and Raj undertake an underground research expedition that turns into a test of how long before they get under each other's skin. Meanwhile, Leonard and Penny argue about money.
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Amy and Bernadette organize a prom to be held atop the guys' apartment complex but Sheldon is leery of all the prom pomp, circumstance and romancing that goes with it.
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Penny entices Leonard to meet with a psychiatrist and the results are surprising; Stuart moves out of the Wolowitz house and Howard and Bernadette find themselves at a loss.
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Dealing with an under-the-weather Sheldon is so draining for Penny, Leonard, and the gang, that they decide to treat themselves to a Sheldon-less weekend.
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Sheldon's grandmother, aka Meemaw, visits and there's friction between her and Amy, which intensifies after the elderly woman blurts out a secret about Sheldon.
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Sheldon and Amy celebrate Valentine's Day with an episode of Fun With Flags; Leonard and Penny feel the pangs of aging; Howard and Bernadette are surprised by what they find in their hot tub.
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The gang learns Bernadette is pregnant and celebrate by singing karaoke. Meanwhile, Wolowitz freaks out over the pregnancy announcement and becomes convinced he must make more money to provide for the baby.
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