Amy and Bernadette accuse former party girl Penny of becoming a party pooper when she lets an email from work impact their girls' weekend in Las Vegas. Meanwhile, the guys brainstorm about inventing something cool.
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Sheldon and Raj undertake an underground research expedition that turns into a test of how long before they get under each other's skin. Meanwhile, Leonard and Penny argue about money.
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Penny's flirtatious sales pitch leaves a doctor-client smitten and the guys must pitch in to help her deal with him, while, Bernadette and Amy debate whether female scientists ought to play the sexuality card.
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Amy and Bernadette organize a prom to be held atop the guys' apartment complex but Sheldon is leery of all the prom pomp, circumstance and romancing that goes with it.
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On Christmas Eve, Amy plans a traditional Victorian dinner, while Raj, Leonard and Howard scramble to remove a pigeon that flew into the clean room at the university.
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Sheldon becomes concerned that his cushy lifestyle is impacting his professional progress and keeping him from achieving scientific renown, so he asks the gang to make life more difficult for him.
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An online troll rips Leonard and Sheldon's published physics paper, so the guys rally to defend the two and expose the bully, while a girls night out leads to Penny, Amy and Bernadette dishing about embarrassing past events.
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Amid the excitement of Stuart reopening his comic-book store, Howard gets some unsettling news; and after teaching Sheldon how to "let it go," Penny doesn't practice what she preaches when she learns something about Amy.
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An experiment designed to make participants fall in love piques Penny and Leonard's interest, so they decide to put it to the test. Meanwhile, Leonard, Amy, Raj and Emily have an encounter with a zombie.
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The Season 11 finale: When Amy's parents and Sheldon's family arrive for the wedding, everybody is focused on making sure all goes according to plan--everyone except the bride and groom.
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In the Season 12 premiere, Sheldon and Amy's honeymoon runs aground in New York, while Penny and Leonard discover they are uncomfortably similar to Amy's parents. Raj insults physicist Neil deGrasse Tyson and starts a twitter war.
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Sheldon and Amy drive themselves crazy trying to figure out what "perfect gift" Leonard and Penny gave them for their wedding. Raj decides he wants to settle down and asks his father to arrange a marriage for him.
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Howard's life gets complicated when Stuart starts bringing his new girlfriend home. Penny and Leonard talk about starting a family while Raj explores an arranged marriage.
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Sheldon won't tell anyone why he's never mentioned Tam, his childhood best friend, so Leonard takes matters into his own hands. Bernadette and Penny take out Raj's fiance, Anu, for dinner to get the skinny on her.
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About
Leonard and Sheldon are brilliant physicists, the kind of ''beautiful minds'' that understand how the universe works. But none of that genius helps them interact with people, especially women. All this begins to change when a free-spirited beauty named Penny moves in next door.
