Herpe, the Love Sore

Stewie is fascinated by the blood oath in The Outlaw Josey Wales and begs Brian to perform the same ritual with him. After some nagging, Brian finally relents. They cut their palms and firmly shake hands, thus becoming blood brothers. The next morning, Stewie wakes up to find his lip has broken out with herpes sores.

Season 12 | Episode 16

Seth MacFarlane

Peter Griffin

Alex Borstein

Lois Griffin

Seth MacFarlane

Stewie Griffin

Mila Kunis

Meg Griffin

Seth Green

Chris Griffin

Seth MacFarlane

Brian Griffin

Seth MacFarlane

Glenn Quagmire

Patrick Warburton

Joe Swanson

Mike Henry

Cleveland Brown